Nuclear Over Houser Effect ( NOE)

Discovered by – Albert Overhouser 1953

It is defined as the change in the intensity of one spin when the transition of another nucleus is perturbed from the equilibrium population.

Nuclear spin that is coupled – gives rise to nuclear over houser effect.

Through space, the coupling is also called dipolar coupling.

It depends on the close proximity of nuclear spins.

It is inversely related to distance as r – 3

allow elucidation of 3D molecular geometry.

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